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Article

Overexpression of Efflux Pump Genes is an Alternative Mechanism in Voriconazole Resistant Aspergillus fumigatus isolates Without Relative Mutations in CYP5A.

Infectious disorders drug targets - 1 Jan 2020

Moazeni Maryam, Aslani Narges, Nabili Mojtaba, Badali Hamid

Abstract excerpt

BACKGROUND: The overexpression of the efflux transporter genes is one of the important mechanisms of resistance in fungal pathogens such as Candida and Aspergillus species. OBJECTIVE: Here, the expression alterations of drug efflux transporter genes were evaluated in non- Cyp51A voriconazole-resistant Aspergillus fumigatus isolates. METHODS: Six A. fumigatus isolates including four voriconazole-resistant isolates...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 31742496
DOI: 10.2174/1871526519666191119123135

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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