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A comprehensive analysis of pneumococcal two-component system regulatory networks

4 Apr 2024

Abstract excerpt

(pneumococcus) encodes 13 two-component systems and a single orphan response regulator, most of which are significant for pneumococcal pathogenicity. Mapping the regulatory networks governed by these systems is key to understand pneumococcal host adaptation. Here we employ a novel bioinformatic approach to predict the regulons of each two-component system based on publicly available whole-genome sequencing data....

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PMID: 38650915
DOI: 10.1093/nargab/lqae039

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