Article
High-quality and -quantity DNA extraction from frozen archival blood clots for genotyping of single-nucleotide polymorphisms.
Genetic testing and molecular biomarkers - 1 Jun 2013
Bank Steffen, Nexø Bjørn Andersen, Andersen Vibeke, Vogel Ulla, Andersen Paal Skytt
Abstract excerpt
BACKGROUND: The recovery of biological samples for genetic epidemiological studies can be cumbersome. Blood clots are routinely collected for serological examinations. However, the extraction of DNA from blood clots can be difficult and often results in low yields. AIM: The aim was to compare the efficiency of commercial purification kits for extracting DNA from long-term frozen clotted blood. METHODS: Serum...
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