Article
A simple genotyping procedure without DNA extraction to identify rare blood donors.
Vox sanguinis - 1 Aug 2015
Silvy M, Brès J-C, Grimaldi A, Movia C, Muriel V, Roubinet F, Chiaroni J, Bailly P
Abstract excerpt
BACKGROUND: Transfusion-induced alloimmunization has severe clinical consequences including haemolytic transfusion reactions, impaired transfused RBCs longevity and greater difficulty in finding compatible blood. Molecular analysis of genomic DNA now permits prediction of blood group phenotypes based on identification of single nucleotide polymorphisms. Implementation of molecular technologies in donor centres...
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