Article

Optimizing storage, high-molecular weight DNA extraction and genome reconstructions from human faecal samples

2025-08-29

Abstract excerpt

Metagenomic sequencing has become an essential tool for assessing the composition and functional potential of microbial communities. However, established metagenomic DNA extraction protocols are limited by trade-offs between universal taxonomic representation, DNA quality, quantity and molecule length, making them mostly unsuitable for 3 rd generation sequencing. <h4>Methods</h4> We assessed the effectiveness o...

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Literature Corpus work: 840a4e21-a1d1-58c1-93e1-d12fed7301e3
DOI: 10.1101/2025.08.27.672560

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