Article
Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort.
PloS one - 1 Jan 2013
Elias-Sonnenschein Lyzel S, Helisalmi Seppo, Natunen Teemu, Hall Anette, Paajanen Teemu, Herukka Sanna-Kaisa, Laitinen Marjo, Remes Anne M, Koivisto Anne M, Mattila Kari M, Lehtimäki Terho, Verhey Frans R J, Visser Pieter Jelle, Soininen Hilkka, Hiltunen Mikko
Abstract excerpt
OBJECTIVES: To understand the relation between risk genes for Alzheimer's disease (AD) and their influence on biomarkers for AD, we examined the association of AD in the Finnish cohort with single nucleotide polymorphisms (SNPs) from top AlzGene loci, genome-wide association studies (GWAS), and candidate gene studies; and tested the correlation between these SNPs and AD markers Aβ(1-42), total tau (t-tau), and...
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