Article
Cytotoxic T-lymphocyte antigen 4 (CTLA4) +49AG and CT60 gene polymorphisms in Alopecia Areata: a case-control association study in the Italian population.
Archives of dermatological research - 1 Sept 2013
Megiorni Francesca, Mora Barbara, Maxia Cristina, Gerardi Martina, Pizzuti Antonio, Rossi Alfredo
Abstract excerpt
Alopecia Areata (AA) is an autoimmune disease characterized by well-circumscribed patches of hair loss especially from the scalp. Cytotoxic T-lymphocyte antigen 4 (CTLA4) gene, a negative regulator of T cells, has been associated with predisposition to most autoimmune disorders. We evaluated two CTLA4 functional single-nucleotide polymorphisms (SNPs) for potential association with Alopecia Areata in an Italian...
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