Article
Association between the CTLA4 +49A/G (rs231775) and CT60 (rs3087243) gene variants with vitiligo: study on a Mexican population.
Anais brasileiros de dermatologia - 1 Jan 2000
Salinas-Santander Mauricio Andrés, Suárez-Valencia Víctor de Jesús, Ángel-Martínez Mayela Del, Kubelis-Lopez David Emmanuel, Zapata-Salazar Natalia Aranza, Ocampo-Garza Jorge Alejandro, Ocampo-Candiani Jorge
Abstract excerpt
BACKGROUND: Vitiligo is characterized by an autoimmune response targeting melanocytes, thus resulting in skin depigmentation. There are several genetic components involved in the development of vitiligo, of which various gene polymorphisms are currently considered as risk factors. For example, the CTLA4 (T-lymphocyte antigen 4) +49A/G (rs231775) and CT60 (rs3087243) gene variants have been associated with a...
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