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Article

Angiotensin converting enzyme inhibitors and Alzheimer disease in the presence of the apolipoprotein E4 allele.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Feb 2014

Qiu Wendy Wei Qiao, Lai Angela, Mon Timothy, Mwamburi Mkaya, Taylor Warren, Rosenzweig James, Kowall Neil, Stern Robert, Zhu Haihao, Steffens David C

Abstract excerpt

OBJECTIVE: The effect of angiotensin converting enzyme (ACE) inhibitors on Alzheimer disease (AD) remains unclear, with conflicting results reported. We studied the interaction of the Apolipoprotein E (ApoE) genotype and ACE inhibitors on AD. METHODS: This was a cross-sectional study of homebound elderly with an AD diagnosis and documentation of medications taken. ApoE genotype was determined. RESULTS: A total of...

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PMID: 23567418
DOI: 10.1016/j.jagp.2012.08.017
PMCID: PMC3873370

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