Article
Pim1 promotes human prostate cancer cell tumorigenicity and c-MYC transcriptional activity.
BMC cancer - 1 Jun 2010
Kim Jongchan, Roh Meejeon, Abdulkadir Sarki A
Abstract excerpt
BACKGROUND: The serine/threonine kinase PIM1 has been implicated as an oncogene in various human cancers including lymphomas, gastric, colorectal and prostate carcinomas. In mouse models, Pim1 is known to cooperate with c-Myc to promote tumorigenicity. However, there has been limited analysis of...
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