Article
A telomerase-independent component of telomere loss in chromatin assembly factor 1 mutants of Arabidopsis thaliana.
Chromosoma - 1 Aug 2013
Jaške Karin, Mokroš Petr, Mozgová Iva, Fojtová Miloslava, Fajkus Jiří
Abstract excerpt
Dysfunction of chromatin assembly factor 1 in FASCIATA mutants (fas) of Arabidopsis thaliana results in progressive loss of telomeric DNA. Although replicative telomere shortening is typically associated with incomplete resynthesis of their ends by telomerase, no change in telomerase activity could be detected in vitro in extracts from fas mutants. Besides a possible telomerase malfunction, the telomere...
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