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Article

KU70 and CAF-1 in Arabidopsis: Divergent roles in rDNA stability and telomere homeostasis.

The Plant journal : for cell and molecular biology - 1 Jun 2024

Závodník Michal, Pavlištová Veronika, Machelová Adéla, Lyčka Martin, Mozgová Iva, Caklová Karolína, Dvořáčková Martina, Fajkus Jiří

Abstract excerpt

Deficiency in chromatin assembly factor-1 (CAF-1) in plants through dysfunction of its components, FASCIATA1 and 2 (FAS1, FAS2), leads to the specific and progressive loss of rDNA and telomere repeats in plants. This loss is attributed to defective repair mechanisms for the increased DNA breaks encountered during replication, a consequence of impaired replication-dependent chromatin assembly. In this study, we...

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PMID: 38493352
DOI: 10.1111/tpj.16718

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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