Article
Genomic insights into the fate of colistin resistance and Acinetobacter baumannii during patient treatment.
Genome research - 1 Jul 2013
Snitkin Evan S, Zelazny Adrian M, Gupta Jyoti, Palmore Tara N, Murray Patrick R, Segre Julia A
Abstract excerpt
Bacterial whole-genome sequencing (WGS) of human pathogens has provided unprecedented insights into the evolution of antibiotic resistance. Most studies have focused on identification of resistance mutations, leaving one to speculate on the fate of these mutants once the antibiotic selective pressure is removed. We performed WGS on longitudinal isolates of Acinetobacter baumannii from patients undergoing colistin...
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