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Article

Genome dynamics of multidrug-resistant Acinetobacter baumannii during infection and treatment.

Genome medicine - 3 Mar 2016

Wright Meredith S, Iovleva Alina, Jacobs Michael R, Bonomo Robert A, Adams Mark D

Abstract excerpt

BACKGROUND: Limited treatment options are available for patients infected with multidrug (MDR)- or pan-drug (PDR)-resistant bacterial pathogens, resulting in infections that can persist for weeks or months. In order to better understand transmission and evolutionary dynamics of MDR Acinetobacter baumannii (Ab) during long-term infection, we analyzed genomes from a series of isolates from individual patients at...

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Identifiers

PMID: 26939581
DOI: 10.1186/s13073-016-0279-y
PMCID: PMC4776386

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