Impact of IL28B on treatment outcome in hepatitis C virus G1/4 patients receiving response-guided therapy with peginterferon alpha-2a (40KD)/ribavirin.

doi:10.1002/hep.24546

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Article

Impact of IL28B on treatment outcome in hepatitis C virus G1/4 patients receiving response-guided therapy with peginterferon alpha-2a (40KD)/ribavirin.

Hepatology (Baltimore, Md.) - 1 Nov 2011

Scherzer Thomas-Matthias, Stättermayer Albert Friedrich, Strasser Michael, Laferl Hermann, Maieron Andreas, Stauber Rudolf, Datz Christian, Dulic-Lakovic Emina, Steindl-Munda Petra, Hofer Harald, Ferenci Peter

Abstract excerpt

UNLABELLED: The IL28B genotype is the most important pretreatment predictor of treatment outcome in patients with chronic hepatitis C. The impact of the rs12979860 genotype on relapse was retrospectively evaluated in genotype 1/4 patients who received response-guided therapy with peginterferon alpha-2a 180 μg/week plus ribavirin 1,000/1,200 mg/day in a large, randomized, multicenter study. Patients with a rapid...

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PMID: 22006276
DOI: 10.1002/hep.24546

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