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Article

Selective neurodegeneration, neuropathology and symptom profiles in Huntington's disease.

Advances in experimental medicine and biology - 1 Jan 2012

Waldvogel Henry J, Thu Doris, Hogg Virginia, Tippett Lynette, Faull Richard L M

Abstract excerpt

Huntington's disease (HD) is an autosomal dominant inherited neurodegenerative disease caused by a CAG repeat expansion in exon 1 of the Huntington gene (HD) also known as IT15. Despite the disease being caused by dysfunction ofa single gene, expressed as an expanded polyglutamine in the huntingtin protein, there is a major variability in the symptom profile of patients with Huntington's disease as well as great...

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PMID: 23560309
DOI: 10.1007/978-1-4614-5434-2_9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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