Article
No effect of the estrogen receptor α gene polymorphisms in the etiology of precocious puberty in girls.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Apr 2013
Lee H S, Kim Y J, Hwang J S
Abstract excerpt
Estrogen plays a crucial role in the development and function in reproductive physiology. Estrogens regulate cellular activity through binding to estrogen receptor α (ERα) and β (ERβ). ERα polymorphisms have been associated with changes in age at menarche, menopause onset, and fertility. The aim of this study is to investigate the relationship of ERα gene polymorphisms with central precocious puberty (CPP) in...
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