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Article

A novel mutation of estrogen receptor gene detected in girls with precocious puberty.

Yi chuan xue bao = Acta genetica Sinica - 1 Oct 2005

Li Bing, Liu Li, Fu Xin, Zhou Wen-Qu, Zou Dong-Ting, Zhao Xiao-Yuan, Cai Yan-Na, Tu Hong-Bin, Liu Qi-Cai, Chen Yao-Yong

Abstract excerpt

Female precocious puberty is caused by premature activation of the hypothalamic-pituitary-gonadal axis, exposure to exogenous sex steroid hormones, and the presence of endogenous sex steroids caused by various factors. Estrogen is the final key factor to start onset of puberty. However,in some cases of precocious puberty in girls estrogen elevation could not be detected. The raised sensitivity of estrogen...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16252695

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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