Article
[Study on the association between estrogen receptor-alpha gene polymorphisms and pubertal skeletal developmental status in China].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 Jun 2007
Yang Li-chen, Piao Jian-hua, Dong Jie, Huang Zhen-wu, Zhang Qian, Ma Guan-Sheng
Abstract excerpt
OBJECTIVE: To investigate the association between estrogen receptor-alpha (ER-alpha) gene polymorphisms, pubertal bone mineral density (BMD) and bone turnover markers, to better understand the frequencies of ER-a genotypes. METHODS: The ER-alpha Pvu II and Xba I genotypes were determined by PCR-RFLP in 158 healthy adolescent girls (12-14 years old) while BMD was measured by dual-energy X-ray absorptiometry...
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