Article
Polymorphism analysis of estrogen receptor β Gene RsaI and AluI in girls with idiopathic central precocious puberty: investigating the relationship and implications for early risk prediction.
Frontiers in endocrinology - 1 Jan 2026
Liu Peipei, Dong Guoqing, Li Mingzhu, Huang Miao, Lu Xiyan, Li Jianxu
Abstract excerpt
Objective: To investigate the association between estrogen receptor β (ERβ) gene RsaI (rs1256049) and AluI (rs4986938) polymorphisms and the risk of idiopathic central precocious puberty (ICPP) in girls, and to provide potential molecular genetic references for early risk prediction and individualized management of ICPP. Methods: A total of 100 girls with ICPP from the Pediatric Endocrinology Clinic and Inpatient...
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