Genome-wide association study evaluating single-nucleotide polymorphisms and outcomes in patients with advanced stage serous ovarian or primary peritoneal cancer: An NRG Oncology/Gynecologic Oncology Group study.

doi:10.1016/j.ygyno.2017.08.024

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Genome-wide association study evaluating single-nucleotide polymorphisms and outcomes in patients with advanced stage serous ovarian or primary peritoneal cancer: An NRG Oncology/Gynecologic Oncology Group study.

Gynecologic oncology - 1 Nov 2017

Moore Kathleen N, Tritchler David, Kaufman Kenneth M, Lankes Heather, Quinn Michael C J, Van Le Linda, Berchuck Andrew, Backes Floor J, Tewari Krishnansu S, Lee Roger B, Kesterson Joshua P, Wenham Robert M, Armstrong Deborah K, Krivak Thomas C, Bookman Michael A, Birrer Michael J

Abstract excerpt

OBJECTIVE: This study evaluated single nucleotide polymorphisms (SNPs) associated with progression free (PFS) and overall survival (OS) in patients with advanced stage serous EOC. METHODS: Patients enrolled in GOG-172 and 182 who provided specimens for translational research and consent were included. Germline DNA was evaluated with the Illumina's HumanOMNI1-Quad beadchips and scanned using Illumina's iScan...

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Identifiers

PMID: 28935272
DOI: 10.1016/j.ygyno.2017.08.024
PMCID: PMC5706110

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