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Genetics of Microscopic Polyangiitis in the Japanese Population

1 Jan 2012

Abstract excerpt

The epidemiology of ANCA-associated vasculitis is substantially different between Caucasians and Japanese, which may be related to differences in genetic backgrounds. In this review, I discussed our findings on the genetics of microscopic polyangiitis (MPA) in Japanese. Analysis of HLA genes revealed a significant increase in the HLA-DRB1*09:01-DQB1*03:03 haplotype MPA. This is one of the most frequent haplotypes...

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PMID: 23555527
DOI: 10.3400/avd.ra.12.00062

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