Article
A copy number variant at the KITLG locus likely confers risk for canine squamous cell carcinoma of the digit.
PLoS genetics - 1 Mar 2013
Karyadi Danielle M, Karlins Eric, Decker Brennan, vonHoldt Bridgett M, Carpintero-Ramirez Gretchen, Parker Heidi G, Wayne Robert K, Ostrander Elaine A
Abstract excerpt
The domestic dog is a robust model for studying the genetics of complex disease susceptibility. The strategies used to develop and propagate modern breeds have resulted in an elevated risk for specific diseases in particular breeds. One example is that of Standard Poodles (STPOs), who have increased risk for squamous cell carcinoma of the digit (SCCD), a locally aggressive cancer that causes lytic bone lesions,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.