Article
Noninvasive ultrasound molecular imaging of the effect of statins on endothelial inflammatory phenotype in early atherosclerosis.
PloS one - 1 Jan 2013
Khanicheh Elham, Mitterhuber Martina, Xu Lifen, Haeuselmann Stéphanie P, Kuster Gabriela M, Kaufmann Beat A
Abstract excerpt
BACKGROUND/OBJECTIVES: Inflammatory changes on the endothelium are responsible for leukocyte recruitment to plaques in atherosclerosis. Noninvasive assessment of treatment-effects on endothelial inflammation may be of use for managing medical therapy and developing novel therapies. We hypothesized that molecular imaging of vascular cell adhesion molecule-1 (VCAM-1) with contrast enhanced ultrasound (CEU) could...
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