Article
Bladder cancer SNP panel predicts susceptibility and survival.
Human genetics - 1 Jun 2009
Andrew Angeline S, Gui Jiang, Sanderson Arthur C, Mason Rebecca A, Morlock Elaine V, Schned Alan R, Kelsey Karl T, Marsit Carmen J, Moore Jason H, Karagas Margaret R
Abstract excerpt
Bladder cancer is the fourth most common malignancy in men and the eighth most common in women in western countries. Single nucleotide polymorphisms (SNPs) in genes that regulate telomere maintenance, mitosis, inflammation, and apoptosis have not been assessed extensively for this disease. Using a population-based study with 832 bladder cancer cases and 1,191 controls, we assessed genetic variation in relation to...
Topics
- Adult
- Aged
- Alleles
- Case-Control Studies
- DNA, Neoplasm
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged