Article
Phenotypic and molecular differences between rats selectively bred to voluntarily run high vs. low nightly distances.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Jun 2013
Roberts Michael D, Brown Jacob D, Company Joseph M, Oberle Lauren P, Heese Alexander J, Toedebusch Ryan G, Wells Kevin D, Cruthirds Clayton L, Knouse John A, Ferreira J Andries, Childs Thomas E, Brown Marybeth, Booth Frank W
Abstract excerpt
The purpose of the present study was to partially phenotype male and female rats from generations 8-10 (G8-G10) that had been selectively bred to possess low (LVR) vs. high voluntary running (HVR) behavior. Over the first 6 days with wheels, 34-day-old G8 male and female LVRs ran shorter distances (P < 0.001), spent less time running (P < 0.001), and ran slower (P < 0.001) than their G8 male and female HVR...
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