Article
Do mice bred selectively for high locomotor activity have a greater reliance on lipids to power submaximal aerobic exercise?
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Jul 2012
Templeman Nicole M, Schutz Heidi, Garland Theodore, McClelland Grant B
Abstract excerpt
Patterns of fuel use during locomotion are determined by exercise intensity and duration, and are remarkably similar across many mammalian taxa. However, as lipids have a high yield of ATP per mole and are stored in large quantities, their use should be favored in endurance-adapted animals. To examine the capacity for alteration or differential regulation of fuel-use patterns, we studied two lines of mice that...
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