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Article

Intrinsic aerobic capacity correlates with greater inherent mitochondrial oxidative and H2O2 emission capacities without major shifts in myosin heavy chain isoform.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Nov 2012

Seifert Erin L, Bastianelli Mark, Aguer Céline, Moffat Cynthia, Estey Carmen, Koch Lauren G, Britton Steven L, Harper Mary-Ellen

Abstract excerpt

Exercise capacity and performance strongly associate with metabolic and biophysical characteristics of skeletal muscle, factors that also relate to overall disease risk. Despite its importance, the exact mechanistic features that connect aerobic metabolism with health status are unknown. To explore this, we applied artificial selection of rats for intrinsic (i.e., untrained) aerobic treadmill running to generate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22995392
DOI: 10.1152/japplphysiol.01475.2011
PMCID: PMC3524658

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