Article
Variant form of STAT4 is associated with primary Sjögren's syndrome.
Genes and immunity - 1 Apr 2008
Korman B D, Alba M I, Le J M, Alevizos I, Smith J A, Nikolov N P, Kastner D L, Remmers E F, Illei G G
Abstract excerpt
Single nucleotide polymorphisms in the STAT4 gene have recently been shown to be associated with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Primary Sjögren's syndrome (pSS) is a related autoimmune disease thought to have a pathogenesis similar to these diseases. To test the hypothesis that the variant haplotype of STAT4 seen in RA and SLE is also associated with pSS, we genotyped rs7574865,...
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