Lack of association of vitamin D receptor gene polymorphisms/haplotypes in Sjögren's syndrome.

doi:10.1007/s10067-014-2639-6

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Article

Lack of association of vitamin D receptor gene polymorphisms/haplotypes in Sjögren's syndrome.

Clinical rheumatology - 1 Feb 2015

Zilahi Erika, Chen Ji-Qing, Papp Gábor, Szántó Antónia, Zeher Margit

Abstract excerpt

The vitamin D is involved in a wide variety of biological processes including bone metabolism, modulation of the immune response, and regulation of cell proliferation and differentiation. Vitamin D has several immunomodulatory effects through vitamin D receptor (VDR). A series of common single-nucleotide polymorphisms (SNPs) in the vitamin D receptor gene have been linked to numerous of diseases, including...

Topics

Adult
Aged
Aged, 80 and over
Female
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Genotype
Haplotypes
Humans
Hungary
Male
Middle Aged
Polymorphism, Genetic
Receptors, Calcitriol
Sjogren's Syndrome

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PMID: 24803230
DOI: 10.1007/s10067-014-2639-6

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