Article
Association of E-cadherin (CDH1) gene polymorphisms and gastric cancer risk.
World journal of gastroenterology - 21 Jul 2010
Al-Moundhri Mansour S, Al-Khanbashi Manal, Al-Kindi Mohammed, Al-Nabhani Maryam, Burney Ikram A, Al-Farsi Abdulaziz, Al-Bahrani Bassim
Abstract excerpt
AIM: To investigate the associations between CDH1 gene polymorphisms and gastric cancer (GC) risk predisposition. METHODS: We analyzed four CDH1 polymorphisms (+54 T>C, -160 C>A, -616 G>C, -3159 T>C) in an Omani population, by extraction of genomic DNA from the peripheral blood of 192 patients with GC and 170 control participants and performed CDH1 genotyping using DNA sequencing. RESULTS: CDH1 -160 -AA genotype...
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