Article
Analysis of E-cadherin (CDH1) Gene Polymorphism and Its Association with Cervical Cancer Risk in Bangladeshi Women.
Asian Pacific journal of cancer prevention : APJCP - 1 Jul 2023
Rahman Md Abdur, Hasan Md Mehedi, Hossain Amir, Alam Khan Monjurul, Sultana Razia, Mazid Md Abdul, Rahman Md Mustafizur
Abstract excerpt
BACKGROUND: E-cadherin (CDH1), a tumor suppressor gene, encodes a transmembrane glycoprotein that helps in maintaining squamous epithelium integrity of the cervix. We aimed to investigate the association between -160C/A genetic polymorphism in CDH1 and the risk of cervical cancer in Bangladeshi females. METHOD: The present case-control study included 117 cervical cancer cases and 147 age-matched controls. The...
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