Article
Genetic variants in microRNA biogenesis pathway genes are associated with semen quality in a Han-Chinese population.
Reproductive biomedicine online - 1 Apr 2012
Qin Yufeng, Xia Yankai, Wu Wei, Han Xiumei, Lu Chuncheng, Ji Guixiang, Chen Daozhen, Wang Honghua, Song Ling, Wang Shoulin, Wang Xinru
Abstract excerpt
MicroRNA biogenesis genes have been confirmed involved in lots of diseases. This study evaluated the role of genetic variants in microRNA biogenesis genes in semen quality and idiopathic male infertility. Seven single-nucleotide polymorphisms (SNP) of DICER1 (rs13078, rs1057035 and rs12323635) and DROSHA (rs10719, rs2291109, and ) were determined by TaqMan probes and SNPstream in 667 eligible...
