Article
Association between loss-of-function mutations in the filaggrin gene and self-reported food allergy and alcohol sensitivity.
International archives of allergy and immunology - 1 Jan 2013
Linneberg Allan, Fenger Runa V, Husemoen Lise-Lotte N, Thuesen Betina H, Skaaby Tea, Gonzalez-Quintela Arturo, Vidal Carmen, Carlsen Berit C, Johansen Jeanne D, Menné Torkil, Stender Steen, Melgaard Michael, Szecsi Pal B, Berg Nikolaj D, Thyssen Jacob P
Abstract excerpt
BACKGROUND: Loss-of-function mutations of the filaggrin (FLG) gene cause an impaired skin barrier and increase the risk of atopic dermatitis. Interestingly, FLG mutations have also been found to be associated with a high risk of peanut allergy. OBJECTIVE: We investigated the association of FLG mutations with self-reported food allergy, symptoms of oral allergy syndrome (OAS), and alcohol sensitivity. METHODS: A...
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