Article
[Relationship between core promoter mutation, clinical features and virus replication in HBV carriers].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Mar 2005
Dai Er-hei, Liu Heng-jun, Song Ya-jun, Chen Cui-ying, Yang Rui-fu
Abstract excerpt
OBJECTIVE: To elucidate the relationship between HBV core promoter mutation and clinical features as well as its effects on serum e system and viral replication. METHODS: Semi-nested mutation specific PCR (msPCR) was employed for detecting core promoter mutation at nt 1 762-1 764 in 97 patients with HBV infection. RESULTS: The msPCR method was demonstrated to be specific and reliable for the mutation detection by...
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