Article
Ectopic expression of syntaxin3 affects behaviors of B16 melanoma by controlling actin dynamics.
Cell structure and function - 1 Jan 2013
Shono Michiko, Yoshioka Ryosuke, Chatani Yoshimitsu, Hirai Yohei
Abstract excerpt
The melanin granules are synthesized in melanocytes in the epidermal basal layer and the hair matrix. For the effective passage of melanin granules to the adjacent keratinocytes, melanocytes utilize unique cytoplasmic delivery system in which cytoskeletal network is prominently involved. Here, we show that the t-SNARE protein syntaxin3, a member of a family of key mediators of the cytoplasmic vesicle fusion and...
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