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Article

Influence of CYP2D6 and CYP2C19 gene variants on antidepressant response in obsessive-compulsive disorder.

The pharmacogenomics journal - 1 Apr 2014

Brandl E J, Tiwari A K, Zhou X, Deluce J, Kennedy J L, Müller D J, Richter M A

Abstract excerpt

Numerous studies have reported on pharmacogenetics of antidepressant response in depression. In contrast, little is known of response predictors in obsessive-compulsive disorder (OCD), a disorder with among the lowest proportion of responders to medication (40-60%). Our study is the largest investigation to date (N=184) of treatment response and side effects to antidepressants in OCD based on metabolizer status...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23545896
DOI: 10.1038/tpj.2013.12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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