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Article

Pharmacogenetics of obsessive-compulsive disorder: Investigations of intragenic and regulatory region genetic variations.

Progress in neuro-psychopharmacology & biological psychiatry - 2 Apr 2025

Zai Gwyneth, Zai Clement C, Gonçalves Vanessa F, Wigg Karen, Lochner Christine, Stein Dan J, Mathews Carol A, Kennedy James L, Richter Margaret A

Abstract excerpt

Few pharmacogenetic studies on the use of genetic variations to predict antidepressant response in obsessive-compulsive disorder (OCD) have been published. This study expanded on the limited literature on single nucleotide polymorphisms (SNPs) across previously identified putative susceptibility genes for OCD, by incorporating known functional regulatory elements for all genes of interest. We investigated 17 SNPs...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40054571
DOI: 10.1016/j.pnpbp.2025.111315

Genes

FAIM2
SLITRK5

Provenance

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