Article
TDP-43 frontotemporal lobar degeneration and autoimmune disease.
Journal of neurology, neurosurgery, and psychiatry - 1 Sept 2013
Miller Zachary A, Rankin Katherine P, Graff-Radford Neill R, Takada Leonel T, Sturm Virginia E, Cleveland Clare M, Criswell Lindsey A, Jaeger Philipp A, Stan Trisha, Heggeli Kristin A, Hsu Sandy Chan, Karydas Anna, Khan Baber K, Grinberg Lea T, Gorno-Tempini Maria Luisa, Boxer Adam L, Rosen Howard J, Kramer Joel H, Coppola Giovanni, Geschwind Daniel H, Rademakers Rosa, Seeley William W, Wyss-Coray Tony, Miller Bruce L
Abstract excerpt
BACKGROUND: The aetiology and pathogenesis of non-genetic forms of frontotemporal dementia (FTD) is unknown and even with the genetic forms of FTD, pathogenesis remains elusive. Given the association between systemic inflammation and other neurodegenerative processes, links between autoimmunity a...
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