Article
Complete assignment of the methionyl carbonyl carbon resonances in switch variant anti-dansyl antibodies labeled with [1-13C]methionine.
Biochemistry - 8 Jan 1991
Kato K, Matsunaga C, Igarashi T, Kim H, Odaka A, Shimada I, Arata Y
Abstract excerpt
A 13C NMR study is reported of switch variant anti-dansyl antibodies developed by Dangl et al. [(1982) Cytometry 2, 395-401], who had used the fluorescence-activated cell sorter to select and clone these variants. These switch variant antibodies possess the identical VH, VL, and CL domains in conjunction with different heavy chain constant regions. In the present study, switch variant antibodies of IgG1, IgG2a,...
Topics
- Amino Acid Sequence
- Carbon Isotopes
- Cell Line
- Dansyl Compounds
- Genetic Variation
- Humans
- Immunoglobulin Fab Fragments
- Immunoglobulin G
- Immunoglobulin Heavy Chains
- Immunoglobulin Light Chains