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The role of the ubiquitin proteasome system in lymphoma

27 Mar 2013

Abstract excerpt

The ubiquitin-proteasome system (UPS) maintains the integrity of cellular processes by controlling protein degradation pathways. The role of the UPS in proliferation, cell cycle, differentiation, DNA repair, protein folding, and apoptosis is well documented, and a wide range of protein activities in these signaling pathways can be manipulated by UPS inhibitors, which include many anti-cancer agents. Naturally...

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PMID: 23541070
DOI: 10.1016/j.critrevonc.2013.02.005

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