The formation of mispairs by 8-oxyguanine as a pathway of mutations induced by irradiation and oxygen radicals.

doi:10.1002/jmr.300030105

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Article

The formation of mispairs by 8-oxyguanine as a pathway of mutations induced by irradiation and oxygen radicals.

Journal of molecular recognition : JMR - 1 Feb 1990

Poltev V I, Shulyupina N V, Bruskov V I

Abstract excerpt

Guanine conversion to 8-oxyguanine (OG) was induced by irradiation and oxygen radicals. The pathways of mutations caused by such DNA damage have been considered. Minima of interaction energies of OG with nucleic acid bases are revealed via classical potential function calculations. The minima exi...

Topics

Base Composition
DNA
DNA Damage
Free Radicals
Guanine
Models, Molecular
Mutation
Oxygen
Thermodynamics

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