Article
[Under what conditions does G.C Watson-Crick DNA base pair acquire all four configurations characteristic for A.T Watson-Crick DNA base pair?].
Ukrains'kyi biokhimichnyi zhurnal (1999 ) - 1 Jan 2000
Brovarets' O O
Abstract excerpt
At the MP2/6-311++G(2df,pd)//B3LYP/6-311++G(d,p) level of theory it was established for the first time, that the Löwdin's G*.C* DNA base pair formed by the mutagenic tautomers can acquire, as the A-T Watson-Crick DNA base pair, four biologically important configurations, namely: Watson-Crick, reverse Watson-Crick, Hoogsteen and reverse Hoogsteen. This fact demonstrates rather unexpected role of the...
Topics
- Adenine
- Base Pairing
- Cytosine
- DNA
- Guanine
- Hydrogen Bonding
- Models, Molecular
- Mutation
- Nucleic Acid Conformation
- Protons
- Stereoisomerism
- Thermodynamics