Article
GC-->CG transversion mutation might be caused by 8-oxoguanine oxidation product.
Nucleic acids symposium series - 1 Jan 2000
Kino K, Sugiyama H
Abstract excerpt
Oxidation of d(A6GGA6)/d(T6CCT6) with sensitizer under different UV irradiation periods was examined. Enzymatic digestion of photolysate revealed that the amount of 8-oxoG initially increased with decrease of G and then decreased with the formation of Iz. In order to investigate whether Iz was fo...
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