Article
[Efficacy of radioprotectors and gene mutations following 2-deoxyribosyl damage. Computer modeling].
Radiatsionnaia biologiia, radioecologiia - 1 Jan 2000
Kuzurman P A, Sharpatyĭ V A
Abstract excerpt
The fundamental new universal method of evaluation of the interaction between macroradical and radioprotector (the access window method) is presented here. It's based on the modelling phenomenon of molecule penetration to the active centre of macromolecule structure through the functional groups free "window". The steric modelling of the B-DNA structure fragments allowed to measure the conformation parameters of...
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