Article
Radiation-induced long-lived radicals which cause mutation and transformation.
Mutation research - 12 Oct 1998
Koyama S, Kodama S, Suzuki K, Matsumoto T, Miyazaki T, Watanabe M
Abstract excerpt
Using electronic spin resonance (ESR), we found a new type of radical with a long life-time in cells (T1/2>20 h) and which may play a more important role in the induction of mutation and transformation than either the active, short-lived, H, or OH radicals. When cells were treated with dimethyl sulfoxide (DMSO) and l-ascorbic acid (AsA) just before irradiation, the short-lived radicals were well-scavenged. On the...
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