Article
Identifying and classifying trait linked polymorphisms in non-reference species by walking coloured de bruijn graphs.
PloS one - 1 Jan 2013
Leggett Richard M, Ramirez-Gonzalez Ricardo H, Verweij Walter, Kawashima Cintia G, Iqbal Zamin, Jones Jonathan D G, Caccamo Mario, Maclean Daniel
Abstract excerpt
Single Nucleotide Polymorphisms are invaluable markers for tracing the genetic basis of inheritable traits and the ability to create marker libraries quickly is vital for timely identification of target genes. Next-generation sequencing makes it possible to sample a genome rapidly, but polymorphism detection relies on having a reference genome to which reads can be aligned and variants detected. We present...
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