Article
Leveraging a phased pangenome for haplotype design of hybrid potato.
Nature - 1 Apr 2025
Cheng Lin, Wang Nan, Bao Zhigui, Zhou Qian, Guarracino Andrea, Yang Yuting, Wang Pei, Zhang Zhiyang, Tang Dié, Zhang Pingxian, Wu Yaoyao, Zhou Yao, Zheng Yi, Hu Yong, Lian Qun, Ma Zhaoxu, Lassois Ludivine, Zhang Chunzhi, Lucas William J, Garrison Erik, Stein Nils, Städler Thomas, Zhou Yongfeng, Huang Sanwen
Abstract excerpt
The tetraploid genome and clonal propagation of the cultivated potato (Solanum tuberosum L.)1,2 dictate a slow, non-accumulative breeding mode of the most important tuber crop. Transitioning potato breeding to a seed-propagated hybrid system based on diploid inbred lines has the potential to greatly accelerate its improvement3. Crucially, the development of inbred lines is impeded by manifold deleterious...
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