Article
Importance of PdpC, IglC, IglI, and IglG for modulation of a host cell death pathway induced by Francisella tularensis.
Infection and immunity - 1 Jun 2013
Lindgren Marie, Eneslätt Kjell, Bröms Jeanette E, Sjöstedt Anders
Abstract excerpt
Modulation of host cell death pathways appears to be a prerequisite for the successful lifestyles of many intracellular pathogens. The facultative intracellular bacterium Francisella tularensis is highly pathogenic, and effective proliferation in the macrophage cytosol leading to host cell death is a requirement for its virulence. To better understand the prerequisites of this cell death, macrophages were...
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