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Article

Expression of IglC is necessary for intracellular growth and induction of apoptosis in murine macrophages by Francisella tularensis.

Microbial pathogenesis - 1 Nov 2004

Lai Xin-He, Golovliov Igor, Sjöstedt Anders

Abstract excerpt

Francisella tularensis is a facultative intracellular bacterium capable of inducing apoptosis in murine macrophages. In a previous study, an iglC null mutant of F. tularensis live vaccine strain LVS was generated by allelic replacement and in the current study this iglC mutant was successfully complemented in trans. We characterized the capacity of this iglC mutant and the complemented strain to induce macrophage...

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PMID: 15519043
DOI: 10.1016/j.micpath.2004.07.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Expression of IglC is necessary for intracellular growth and induction of apoptosis in murine macrophages by Francisella tularensis.PMID 15519043Read ↗

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